Mallorie TOURBIN

I focus my research work on the elaboration of particle suspensions or dry powders and on the understanding of the links between the parameters of the generation/treatment processes and the functional properties of the materials. My studies always include an important part on the development of characterization techniques for the physical (size, morphology, structuration, viscosity, etc.) and chemical (composition, crystallinity, etc.) properties of the particles and media studied.

My projects mainly concern:

• Synthesis, treatment and shaping of nanoparticles for biomedical applications (drug delivery, bone prostheses)
• Understanding and optimization of particulate processes: spray-drying, wet grinding, precipitation
• Agglomeration behaviour of the (nano)particles in suspension during particulate processes
• Characterization of the effect of the physico-chemical and hydrodynamical conditions on the behaviour of (nano)particles in suspensions

Research applications:

• Pharmaceutical or biomedical applications: e.g. production of nanosystems for the vectorization of active ingredients

Current study: Innovative process for the formulation of multifunctional drugs nanocarriers based on mesoporous silica nanoparticles – PhD of Lucas Ruffel (2019)

• Food and nutraceutics: encapsulation of antioxidant molecules

Current study: Nanoencapsulation of active ingredients by spray-drying – PhD of Daniel Tobon Velez (ongoing)

• Biomaterials: e.g. tailoring of powder for the coating of bone prostheses (ANR Innov’HAP) or for the 3D printing of pieces for bone reconstruction (Projet Européen DOC-3D-PRINTING). 

Current study: Tailoring calcium phosphate powder properties for 3D-laser printing – PhD of Pedro Navarrete-Segado (2021)

Research supervision

• PhD students:  Yanping Liu (2010), Lucas Ruffel (2019), Antoine Marie (2020), Pedro Jesús Navarrette Segado (2021), Daniel Santiago Tobón Vélez (ongoing).
• Post-docs fellows: Nicolas Abi Chebel, Pierre Gras, Marguerite d’Olce

Teaching activities

Chemical engineering: process conception and pilots sizing, industrial chemistry/ Chemical kinetics / Particulate processing, encapsulation technologies

Responsible for Master degree “Production processes and quality of Health products”.

Collaborators

Academic partners: CIRIMAT, LCA, LCC, PHENIX, SQPOV

Industries and private organisms: Urodelia, Bertin Technologies, Winlight System, CEA, Unither Pharmaceuticals, Lucas Meyer

International collaborations: Universidad del Sur (Bahia Blanca, Argentina), Universidad Michoacana de San Nicolás de Hidalgo (Morelia, Mexico), Universidad Nacional Autonoma de Mexico (Mexico, Mexico)